The Invisible Sculptor of COVID-19 Revealed

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A team from the University of California, Riverside has made significant progress in understanding the SARS-CoV-2 virus by studying the M protein. Their research revealed how this protein helps the virus achieve its spherical shape, offering potential new avenues for viral intervention. Credit: SciTechDaily.com, being a recent example.

Kuhlman was joined in the research by fellow-UCR physicists Roya Zandi and Umar Mohideen. Kuhlman was charged with making the M proteins. Mohideen, a distinguished professor of physics and astronomy, used atomic force microscopy and cryogenic electron microscopy to measure how the M protein interacts with the membrane. Zandi, an expert on virus assembly and a professor of physics and astronomy, developed simulations of how the M proteins interact with each other and with the membrane.

The research was supported by a grant from the University of California Office of the President to investigate how the COVID-19 virus assembles itself.

 

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