Reviewed by Danielle Ellis, B.Sc.Oct 30 2023 The surface of the nanoparticles is engineered to host any biological molecules of choice, making it possible to tailor the nanoparticles for a wide array of applications, ranging from targeted drug delivery to neutralizing biological agents.
The modular nanoparticles consist of biodegradable polymer cores coated with genetically modified cell membranes. The key to their modular design is a pair of synthetic proteins, known as SpyCatcher and SpyTag, that are specifically designed to spontaneously-;and exclusively-;bind with each other. This pair is commonly used in biological research to combine various proteins.
Related StoriesTo create the modular nanoparticles, the researchers first genetically engineered human embryonic kidney 293 cells-;a commonly used cell line in biological research-;to express SpyCatcher proteins on their surface. The cell membranes were then isolated, broken into smaller pieces, and coated onto biodegradable polymer nanoparticles.
Technology Technology Latest News, Technology Technology Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Source: NewsMedical - 🏆 19. / 71 Read more »