A study from Mass General Brigham indicates that inheriting Alzheimer’s disease risk from the maternal side is linked to higher amyloid levels in the brain, suggesting potential targets for early prevention in Alzheimer’s disease.
“Some people decide not to pursue a formal diagnosis and attribute memory loss to age, so we focused on a memory loss and dementia phenotype,” Yang said. Yang noted one limitation of the study is some participants’ parents died young, before they could potentially develop symptoms of cognitive impairment. He said social factors like access to resources and education may have also played a role in when someone acknowledged cognitive impairment and if they were ever formally diagnosed.
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