University of GothenburgJul 1 2024 . The AI model is faster and better at finding abnormalities than the current semi-manual method.
However, the data from the mass spectrometer measurement must be carefully analyzed by humans to work out the structure from the glycan fragmentation. This process can take anywhere from hours to days for each sample and can only be carried out with high confidence by a small number of experts in the world, as it is essentially detective work learnt over many years.
Researchers at the University of Gothenburg have developed an AI model to automate this detective work. The AI model, named Candycrunch, solves the task in just a few seconds per test. The results are reported in a scientific article in the journal Nature Methods. The training has enabled Candycrunch to calculate the exact sugar structure in a sample in 90 percent of cases." Can find new biomarkers This means that the AI model could soon reach the same levels of accuracy as the sequencing of other biological sequences, such as DNA, RNA or proteins.
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