New advances in DNA technology at CWRU promise to revolutionize genetic testing

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The method rapidly and accurately amplifies very small amounts of DNA, into samples large enough to be used in conventional medical testing, making identification possible with samples that would have otherwise returned poor, or no results.

Researchers at Case Western Reserve University have created a new diagnostic method they say is the holy grail of DNA testing: one that is both fast and accurate, even when using complex DNA sequences.CLEVELAND, Ohio—Case Western Reserve University researchers have developed a new method of DNA testing—one they say could greatly expand its uses in medical research.

depends on the technology that allows researchers to make a lot of DNA from a very small amount, and to do it quickly, without making errors. This new technique, known as AMPLON , offers an alternative to the previously accepted “gold-standard” of PCR, opening the opportunity for more applications in medical diagnosis.

This new method eliminates the need for the amplification machinery to search for new amplification targets, improving both its speed and accuracy at the same time.

 

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