Using a microscopy image and graphic rendering, the artists illustrate a minimal synthetic cell that can sense a directional chemical cue and self-organize in response. Credit: Inoue Lab at Johns Hopkins Medical Institute, created by Shiva Razavi and Turhan Pathan, edited
Scientists at Johns Hopkins Medicine have developed a minimal synthetic cell capable of following external chemical signals and exhibiting a fundamental biological concept known as “symmetry breaking.” This incredible innovation aims to enhance our understanding of cellular movement and devise new methods for transporting drugs within the body.
Finding ways to mimic and control symmetry breaking in synthetic cells has long been considered essential for understanding how cells can survey their chemical environment and rearrange their chemical profile and shape in response.For this study scientists created a giant vesicle with a double-layered membrane —a bare-bones, simplified synthetic cell or protocell made of phospholipids, purified proteins, salts and ATP that provides energy.
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