Gender being less of an issue, body modification at the touch of a button, personal avatars, alien life having different attitudes to, or experiences of gender, it's given some authors that chance to ask 'what if' you weren't restrained either by your own biology or social expectations. The Left Hand of Darkness by Ursula K. Le Guin is a classic example, where humanity meets an alien race that changes gender through its life. Robert A.
Set one year ahead of Discovery, eleven years ahead of The Original Series… and also a hundred years after the established year that the Geneva Convention on Biological Weapons was renewed in Star Trek lore. In doing so, recognising the difference between classic Klingon and later Kilingon as down to an 'augment virus' as established in Discovery. My dad always used to call Star Trek species 'nose aliens,' 'chin aliens,' or 'ear aliens.