Doctors warn of irreversible brain damage from inhaling fentanyl, evidenced by a case reported in BMJ Case Reports where a man developed toxic leukoencephalopathy after snorting the drug. Credit: SciTechDaily.com, after treating a middle-aged man found unresponsive in his hotel room after snorting the drug.
The outlook for those affected generally depends on the extent of white matter injury, explain the report authors: some people will recover fully; others will progressively get worse.In this case, the man had no previous medical problems of any note, and had been unconscious for an unknown period of time in his hotel room, where unidentified crushed pills and a white residue were found on a nearby table.
A drug screen returned negative results, but a separate urine test indicated a very high level of fentanyl, prompting a diagnosis of toxic leukoencephalopathy induced by fentanyl inhalation.Eighteen days later, he remained bedbound and still required tube feeding. He was given several different drugs to treat urinary incontinence, kidney injury, cognitive impairment, suspected opioid withdrawal, pain and agitation, and pneumonia.
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