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When Antibiotics Fail: MIT Scientists Use AI To Target “Sleeper” Bacteria

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AI-driven research is revolutionizing antibiotic discovery by identifying compounds like semapimod, which can combat dormant bacteria and breach the defenses of resistant Gram-negative bacteria. Credit: SciTechDaily.com

Still from a time-lapse microscopy video of E. coli cells treated with semapimod in the presence of SYTOX Blue. Credit: Image courtesy of the researchers“Resistance is happening more over time, and recurring infections are due to this dormancy,” says Jackie Valeri, a formerAbdul Latif Jameel Clinic for Machine Learning in Health) who recently earned her PhD in biological engineering from the Collins Lab.

 

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