Glycoengineered stem cells enhance brain recovery after cardiac arrest, study finds

May 2 2024University of Maryland School of Medicine Researchers at the University of Maryland School of Medicine have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model. The study led by Xiaofeng Jia, BM, MS, PhD, FCCM, Professor of Neurosurgery, found that the application of modified sugar molecules on human neural stem cells improved the likelihood of the therapy's success.

The potential of stem cell therapy to address neurological dysfunction has long been fraught with challenges due to the harsh in vivo microenvironment of the brain; this results in poor stem cell retention and integration at the site of injuries. The treatment also activated the related inflammatory Wnt/β-catenin signaling pathway, which regulates critical aspects of cell function. This upregulated pathway by TProp promotes the transition of stem cells into neurons, the nerve cells responsible for sending and receiving signals from the brain.

Technology Technology Latest News, Technology Technology Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

University of Manchester Researchers Develop New Catalyst with Wide Range of UsesResearchers at The University of Manchester have achieved a groundbreaking advancement in catalyst technology by developing a new catalyst which has been shown to have a wide variety of uses and the potential to streamline catalyzed optimization processes in industry and support new scientific discoveries.
Source: OilandEnergy - 🏆 34. / 68 Read more »