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2,000+ Genetic Signals Linked to Blood Pressure Discovered in Study of Over a Million People

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Science, Space and Technology News 2024

The Queen Mary-led study reveals the most detailed picture yet of genetic contributors to blood pressure. The findings lead to improved polygenic risk scores, which will better predict blood pressure and risk for hypertension.

To understand the genetics of blood pressure, the researchers combined four large datasets from genome-wide association studies of blood pressure and hypertension. After analyzing the data, they found over 2,000 genomic loci linked to blood pressure, including 113 new regions. The analyses also implicated hundreds of previously unreported genes that affect blood pressure.

 

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