Inflammatory bowel disease depletes the microbial ecosystem within the gastrointestinal tract leading to inflammation and metabolic dysfunction. Prebiotics have been shown to alleviate these symptoms by serving as an energy and food source for gut microbes, restoring the microbiome, and alleviating IBD symptomology. Credit: Ariaee A, Koentgen S, Wardill HR, et al.
IBD, encompassing Crohn’s disease, ulcerative colitis, and unclassified IBD, is characterized by chronic inflammation of the digestive tract. Conventional treatments aim to control symptoms and prevent complications. However, they often have limited effectiveness and can come with side effects. Researchers believe that promoting the growth of beneficial bacteria through prebiotics may restore balance in the gut and alleviate IBD symptoms. This hypothesis has been evaluated in a number of clinical studies. More research on humans is needed to fully understand the personalized responses that occur in these IBD patients before clinical recommendations can safely be made.
This approach holds significant promise for improving the lives of patients with IBD. By harnessing the power of gut bacteria, researchers are paving the way for a new generation of treatments that target the root cause of the disease.
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