The American College of Physicians issued new guidelines for Type 2 diabetes treatment, which for the first time recommends the use of GLP-1s and another class of diabetes drugs called SGLT-2s alongside metformin, though this may exacerbate the ongoing drug shortages of several GLP-1s.
In the updated guidelines, the ACP also recommends against the use of DPP-4 inhibitors alongside metformin, because new evidence showed DPP-4s didn’t reduce disease or death.—may be a “significant barrier” in providing patients with access to treatment, according to an accompanying editorial by Fatima Zyed, an internal medicine doctor at Duke University’s Division of General Internal Medicine.