Breaking through new research barriers with iPSC technology

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In this interview, we speak to Keith Olson and Coby Carlson from Fujifilm Cellular Dynamics about their iPSC technology.

Sponsored Content by FUJIFILM Cellular DynamicsFeb 15 2024Reviewed by Aimee Molineux insights from industryDr. Coby CarlsonDr. Keith OlsonFUJIFILM Cellular Dynamics In this interview, we speak to Keith Olson and Coby Carlson from FUJIFILM Cellular Dynamics about their iPSC technology and how it is making breakthroughs in blood-brain barrier research.

Keith Olson: I believe that we were pioneers of iPSC technology in the United States. We successfully brought it to market, commercialized it, and built a business around it. Our reputation is now based on our core expertise, quality, and ability to manufacture at scale for our clients in the pharmaceutical, biotech, and academic sectors.iPSC technology can be used to revolutionize scientific research and cell therapy.

Keith Olson: Everything starts from a core iPS cell bank, and we have developed specific differentiation protocols for each terminal phenotype of the cell. Whether it is a cardiomyocyte, neuron, or hepatocyte, we have a differentiation protocol that takes us from the core stem cell bank to a finished product that customers can purchase and use as an assay-ready sample.

Keith Olson: The system is perfect for 3D modeling because it is a 3D system. It is a multi-layer, multi-cell-type organ or part of an organ, and using it as an organoid or spheroid in a complex model brings you closer to that model system. Building the barrier is crucial, and 3D modeling is the best way to achieve this. Our released product is flexible enough for clients to conduct assays in a Transwell plate or as a spheroid.

Keith Olson: I think anything that any of our competitors, colleagues, friends, and neighbors are doing in this space will help push the field forward. The more vendors and researchers working on creating relevant model systems for humans, the better. With the FDA Modernization Act and the desire for better test systems and models, everyone working together will likely result in better systems and, hopefully, faster, cheaper, and easier drug discovery for companies.

Industrial Scale Cell Engineering - FUJIFILM Cellular Dynamics at SLAS 2023Play On your website, you also offer a variety of resources for your customers, including research posters, webinars, and videos. How important are these resources in building customer relationships? Coby Carlson: Reviews and testimonials are popular among our customers, who are primarily scientists requiring supporting evidence.

 

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