Injectable tissue prosthesis to aid in damaged muscle/nerve regeneration

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Researchers have made significant strides in biomaterial technology and rehabilitation medicine. They've developed a novel approach to healing muscle injury by employing 'injectable tissue prosthesis' in the form of conductive hydrogels and combining it with a robot-assisted rehabilitation system.

, researchers from the Institute of Basic Science in South Korea have made significant strides in biomaterial technology and rehabilitation medicine. They've developed a novel approach to healing muscle injury by employing"injectable tissue prosthesis" in the form of conductive hydrogels and combining it with a robot-assisted rehabilitation system.

Unfortunately, the mechanical properties and rigid nature of existing electronic materials render them incompatible with soft tissues. This leads to friction and potential inflammation, stalling patient rehabilitation. With mechanical properties akin to natural tissues, exceptional tissue adhesion, and injectable characteristics, researchers believe this material offers a novel approach to rehabilitation.Next, the researchers put this novel idea to the test in rodent models. To simulate volumetric muscle loss injury, a large chunk of muscle has been removed from the hind legs of these animals.

Professor SON Donghee added,"In this study, the closed-loop gait rehabilitation system entailing tough injectable hydrogel and stretchable and self-healing sensors could significantly enhance the rehabilitation prospects for patients with neurological and musculoskeletal challenges. It could also play a vital role in precise diagnosis and treatment across various organs in the human body.

 

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