Inflammation and Vitamin B12: Unraveling the Hidden Connection

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A new study identified a compelling link between vitamin B12 deficiency and chronic inflammation, which is linked to several health problems including, diabetes, and neurodegenerative disorders. The research, which was published in theVitamin B12, an essential nutrient with roles in various physiological processes, is known to be critical for overall health.

Rosa M. Lamuela-Raventós, co-corresponding author of the study and Professor of Nutrition, Food Sciences, and Gastronomy at INSA-University of Barcelona and Inés Domínguez López, a predoctoral researcher at the University of Barcelona and co-first author of the study explained the motivations behind the study.

‘Our study found that in general, the more vitamin B12 an individual has, the lower their inflammatory markers are — we call this an inverse relationship’, explained Marta Kovatcheva, a postdoctoral researcher at the Institute for Research in Biomedicine and co-first author of the study. ‘With regards to vitamin B12 deficiency, we must point out that we did not specifically look at deficient individuals in this study. Nevertheless, our results raise some important questions.

Surprisingly, the researchers noted that, unlike humans, mice do not become B12 deficient with age. ‘We didn’t know this before, and it poses the possibility that studying mice could potentially help us understand how we could prevent B12 deficiency in older humans,’ said Kovatcheva.

 

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