Selective removal of aging cells opens new possibilities for treating age-related diseases

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A research team, led by Professor Ja Hyoung Ryu from the Department of Chemistry at UNIST, in collaboration with Professor Hyewon Chung from Konkuk University, has achieved a significant breakthrough in the treatment of age-related diseases. Their cutting-edge technology offers a promising new approach by selectively removing aging cells, without harming normal healthy cells. This groundbreaking development is poised to redefine the future of health care and usher in a new era of targeted therapeutic interventions.

Aging cells, known as senescent cells, contribute to various inflammatory conditions and age-related ailments as humans age. To address this issue, the research team focused on developing a technology that could precisely target and eliminate aging cells, while sparing normal healthy cells.

that selectively target receptors overexpressed in the membranes of aging cells. By leveraging the higher levels of reactive oxygen species found in aging cells, these molecules promote the formation of disulfide bonds and create oligomers that bind together. The research is published in the

 

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