Software analyzes calcium 'sparks' that can contribute to arrhythmia

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A team of UC Davis and University of Oxford researchers have developed an innovative tool: SparkMaster 2. The open-source software allows scientists to analyze normal and abnormal calcium signals in cells automatically.

, is a Sir Henry Wellcome Fellow in the Department of Physiology, Anatomy and Genetics at the University of Oxford. He spent his fellowship year at UC Davis, working with Distinguished Professor Donald M. Bers.

However, the resulting data files are large and challenging to analyze by hand, so customized software analysis tools are essential. The UC Davis SparkMaster 2 team: Donald M. Bers , Manuel F. Navedo , Christopher Y. Ko , Madeline Nieves-Cintron . Credit: UC Davisby Bers and Eckard Picht. Picht is a physician-scientist who worked with Bers, first at Loyola University Chicago and then for a few years at UC Davis. At the time, there was no user-friendly free software that could analyze calcium sparks—a crucial part of their research—so they developed one.

 

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