Pulsed Field Ablation Challenges Conventional Devices in AF

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In the ADVENT trial, pulsed field ablation, a new technology for terminating drug-refractory paroxysmal AF, was noninferior to conventional thermal ablation but had potential advantages.

Catheter ablation

Reddy emphasized that noninferiority for PFA was achieved by operators with little or no experience with this technology, whereas the catheter ablations were delivered by operators who typically had previously performed hundreds of interventions.Procedure Time Faster With PFA "When you look at procedure performance, it is remarkable that the procedure times were statistically significantly shorter for a first-use technology in the hands of multiple operators," Reddy said.

Overall, Reddy believes that the data from ADVENT provide several reasons"to get excited about PFA," including the efficiency of this technique in the context of at least similar efficacy but a potential for fewer adverse events.

 

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