Reviewed by Lily Ramsey, LLMAug 25 2023 This is particularly crucial in the case of cancer, as the stage of cancer development at the time of initial diagnosis significantly influences the patient's prognosis and survival rate. Therefore, regular medical check-ups can ensure better survival and quality of life. However, the multitude of medical examination items makes the experience both loved and loathed.
Recently, a research team from Griffith University published a research article titled "Asymmetrical Obstacles Enable Unilateral Inertial Focusing and Separation in Sinusoidal Microchannel" in the esteemed journal Cyborg and Bionic Systems as part of the China Science and Technology Journal Excellent Action Plan.
Even without considering the erosion effect of the riverbank, the principle of sedimentation towards the convex bank due to the pressure difference and inertia caused by the flow velocity difference is still applicable. This principle is employed in microfluidic channels for cell separation. In curved channels, cells tend to accumulate on the outer side of the bend due to inertia and pressure differences.
Experiment validation Related StoriesSubsequently, they experimentally validated this hypothesis by confirming that the presence of obstacles in the curved microchannel indeed caused cell focusing on one side of the channel. Furthermore, they observed that this unilateral focusing effect was dependent on the size of the cells, indicating the potential to separate cells of different sizes based on this characteristic.