The research team incorporated a type of artificial intelligence called Alpha Fold 2 into the study. The team trained the AI to solve the 3D structure of proteins from the amino acid sequences. Alpha Fold 2 is acreated by Deep Mind, an artificial intelligence company owned by Google.
The Alpha Fold 2 currently has data from over 300,000 models. Researchers evaluated the new structures made available and compared them to the ones currently available. They concluded that Alpha Fold 2 had contributed an additional 25% of high-quality protein structures not previously included in the data.
Although the key role proteins play in disease such as cancer is known, applying AI to the information will allow for a deeper comprehension of the function of proteins at their molecular levels. The structural data about these proteins will help researchers understand the proteins better, and to know what other molecules may interact within the cell. This could allow for the creation of new medication that could interfere with the protein functions when they are altered.
The research includes the thousands of new 3D protein models, and the team is looking forward to the future impact artificial intelligence will have on the discovery of new proteins, which could lead to new treatments.
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Source: newscientist - 🏆 541. / 51 Read more »