A representative for Arbutus did not immediately respond to a request for comment on Acuitas' claims.
The lawsuit is part of a growing web of patent disputes over COVID-19 vaccine technology. Arbutus sued Moderna over its mRNA technology last month, but has not yet sued Pfizer or Acuitas. Pfizer and Moderna were hit with patent lawsuits on Thursday by Alnylam Pharmaceuticals, which argued its own lipid nanoparticle mRNA-delivery technology was "essential" to both of the widely used COVID-19 vaccines.
Pfizer said last month that it expected US$32 billion in revenue from its vaccine this year. Moderna has said its vaccine earned the company $17.7 billion in revenue in 2021.