, opening the doors for others to come in and develop vaccines and treatments.
Companies that use artificial intelligence to suss out molecules for potential drugs are among those looking for an answer to the coronavirus. On Tuesday, Benevolent AI published a letter in, explaining how it found a drug that could be repurposed to fight the coronavirus using artificial intelligence. The most promising choice is a drug called janus kinase inhibitor baricitinib, which is currently used to treat rheumatoid arthritis.
Insilico Medicine, meanwhile, took a different approach by using artificial intelligence to identify six new molecules that might inhibit the spread of the coronavirus inside the body. On Thursday, the company published its findings in Biorxiv, an open access database for papers that have not been vetted. “We are in an unknown territory—that’s one of the reasons we’re publishing,” says Insilico CEO Alex Zhavoronkov.
The goal for both Benevolent AI and Insilico Medicine is to help speed up the search for a solution. Through publishing its findings, Zhavoronkov says, the company can get feedback highlighting potential problems with the molecules, like if one is a known toxin. In the event that one appears promising to medicinal chemists, Zhavoronkov says it can be synthesized in a few weeks, after which testing can begin.
The coronavirus has spread quickly inside of China and has now found its way to nearly 30 countries. Still, the bulk of the virus has affected China. It has a death rate of around 2%, which is so far more deadly than this year’s influenza, but far less deadly than SARS.That’s why government officials and drug companies are moving fast to find a solution to the coronavirus, which first became public at the end of 2019.
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